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Tag: THF


2010-12. Selectivity in Reversed-Phase LC Separations, Part I: Solvent-Type Selectivity

December 1, 2010

Methanol and acetonitrile are the two most popular organic solvents to use in the mobile phase for reversed-phase liquid chromatography (LC) separations. Tetrahydrofuran is also used to a lesser extent. Why are these solvents the most popular ones? Are there alternative solvents that should be tried? This month’s “LC Troubleshooting” […]

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