2012-7. Troubleshooting Basics, Part IV: Peak Shape Problems
What do you do when the peak shape changes? LCGC 30(7) 564-569 (2012) John W. Dolan Erratum: see 30(5)
Read More →What do you do when the peak shape changes? LCGC 30(7) 564-569 (2012) John W. Dolan Erratum: see 30(5)
Read More →When something doesn’t look right in an LC Method, better check it out. LCGC28(10) 866-872 (2010) John W. Dolan
Read More →Look at the big picture. It may not be appropriate to obsess on the details. LCGC28(5) 358-363 (2010) John W. Dolan
Read More →Where to place the blame when something goes wrong. LCGC 27(9) 816-821 (2009) John W. Dolan
Read More →What measurements are required for system suitability? LCGC 27(2) 120-128 (2009) John W. Dolan
Read More →Excess variability is not acceptable in a pharmaceutical method. LCGC 24(12) 1274-1278 (2006) Nastaran Sigari and John W. Dolan Erratum: Note that equation 5 for USP tailing factor is not correct. It should read: TF = w(total)/2*w(front).
Read More →Truly symmetrical peaks are rare. LCGC 21(7) 612-616 (2003) John W. Dolan
Read More →Is a small peak hiding under that tail? Keywords: LCGC 20(7) 594-598 (2002) John W. Dolan
Read More →How does peak tailing affect resolution? LCGC 20(5) 430-436 (2002) John W. Dolan
Read More →Promotional material can be a good source of troubleshooting advice. LCGC 15(11) 1018-1020 (1997) John W. Dolan
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