2014-11. How Much Can I Inject? Part II: Injecting in Solvents Other than Mobile Phase
How large an injection can you make if the injection solvent is not matched to the mobile phase? LCGC 32(11) 854-859 (2014) John W. Dolan
Read More →How large an injection can you make if the injection solvent is not matched to the mobile phase? LCGC 32(11) 854-859 (2014) John W. Dolan
Read More →Why do some peaks front and others don’t in the same method? LCGC 31(12) 992-997 (2013) John W. Dolan
Read More →The solvent chosen for injection can affect the appearance of chromatograpic peaks. LCGC 30(10) 898-902 (2012) Bandar Alshli and John W. Dolan Erratum: (from 30(12): equation 2 should read: w = 4 tR / N^0.5.With this change, all the calculated values of peak widths and recommended injection volumes should be […]
Read More →No matter where liquid chromatography is used, it is never immune to problems. LCGC 30(1) 36-40 (2012) John W. Dolan
Read More →Methanol and acetonitrile are the two most popular organic solvents to use in the mobile phase for reversed-phase liquid chromatography (LC) separations. Tetrahydrofuran is also used to a lesser extent. Why are these solvents the most popular ones? Are there alternative solvents that should be tried? This month’s “LC Troubleshooting” […]
Read More →How to avoid an expensive shot in the dark. LCGC 25(10) 1014-1020 (2007) John W. Dolan
Read More →Getting started on the right foot is important for efficient method development. LCGC 25(7) 632-638 (2007) John W. Dolan
Read More →Where did that ugly peak come from? LCGC 23(8) 738-743 (2005) John W. Dolan
Read More →Does your method have a safety factor? LCGC 23(1) 30-35 (2005) John W. Dolan
Read More →Do your peaks need to go on a diet? LCGC 22(1) 26-30 (2004) John W. Dolan
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