We’ll learn how to find the “sweet spot” in terms of retention for a liquid chromatography separation as well as how much retention change can be expected for a selected change in mobile-phase percent organic or column temperature. LCGC 35(4) 240-245 (2017) John W. Dolan See also 2017-3 and 2017-5 […]
Read More →When considering column efficiency, more is not always better. We look at some ways to quickly estimate the effects of changes in column length and particle diameter rather than trying the experiments in the laboratory. LCGC 35(3) 170-173 (2017) John W. Dolan See also 2017-4 and 2017-5 for remaining articles […]
Read More →How suitable is the column plate number for system suitability testing? LCGC 34(3) 190-197 (2016) John W. Dolan
Read More →Both the volume of the sample injection and the solvent in which the sample is dissolved can affect the appearance of the chromatogram. LCGC 32(10) 780-785 (2014) John W. Dolan
Read More →How can resolution be determined when peak width cannot be measured? LCGC 32(9) 718-725 (2014) John W. Dolan
Read More →A change in the mobile phase strength can be a powerful tool to move peaks in a separation. LCGC 29(1) 28-34 (2011) John W. Dolan
Read More →What measurements are required for system suitability? LCGC 27(2) 120-128 (2009) John W. Dolan
Read More →Trade extra resolution for speed. LCGC 25(11) 1094-1102 (2007) John W. Dolan
Read More →Faster isn’t always better. LCGC 25(8) 704-709 (2007) John W. Dolan
Read More →Different methods require different strategies. LCGC 25(6) 546-552 (2007) John W. Dolan
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