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Tag: pH problems


2016-2. Detective Work, Part IV: Chemical Problems with the Column — Chemical Attack

February 1, 2016

The silica-based packing in reversed-phase columns is not inert. Here we consider what happens when the mobile-phase pH is too high or too low. LCGC 34(2) 106-113 (2016) John W. Dolan

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2009-9. Method or System?

September 1, 2009

Where to place the blame when something goes wrong. LCGC 27(9) 816-821 (2009) John W. Dolan

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1993-10. What’s Wrong with Ethylparaben?

October 1, 1993

Two problems submitted this month have one thing in common — unsatisfactory results when ethylparaben was used as an internal standard. LCGC 11(10) 714-716 (1993) John W. Dolan

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1993-5. Aggressive Mobile Phases — A Case Study

May 1, 1993

When two failures occur at nearly the same time, troubleshooting can be confusing. LCGC 11(5) 344-349 (1993) Daniel H. Marchand, Janice A. Lewis, and John W. Dolan

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