Delivering samples to the analytical column in “clean” mobile phase is important for robust methods and high quality results. LCGC 35(2) 98-103 (2017) Dwight Stoll Note: this is the first installment of “LC Troubleshooting” in the transition period from John Dolan to Dwight Stoll. The pdf contains an editorial page […]
Read More →Different techniques of liquid chromatography (LC) mobile-phase mixing can give different results and have different problems. LCGC 34(6) 400-407 (2016) John W. Dolan
Read More →Are your solvent costs too high? Here are some ideas about how to decrease the amount of mobile phase you use. LCGC 33(10) 752-757 (2015) John W. Dolan
Read More →Small changes in retention time of a liquid chromatography (LC) method are normal. At what point is a problem suggested? Retention time shifts can be frustrating when you can’t figure out if a shift is something you caused or if there is another reason for it. LCGC 32(8) 546-551 (2014) […]
Read More →Can anything be done to correct for baseline drift in gradient separations? LCGC 31(7) 538-543 (2013) John W. Dolan
Read More →How does a change in flow rate affect the separation? LCGC 26(1) 30-36 (2008) John W. Dolan
Read More →Nothing’s magic — peaks move in a regular manner when conditions are changes. LCGC 24(6) 570-578 (2006) John W. Dolan
Read More →What mobile phase conditions will give good results? LCGC 23(7) 662-667 (2005) John W. Dolan
Read More →Changes in retention time can be a key to tracking down LC problems. LCGC 22(12) 1154-1158 (2004) John W. Dolan
Read More →Some tips for transferring a validated liquid chromatography method from one laboratory to another. LCGC 22(6) 524-528 (2004) John W. Dolan
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