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Tag: injection volume


2014-11. How Much Can I Inject? Part II: Injecting in Solvents Other than Mobile Phase

November 1, 2014

How large an injection can you make if the injection solvent is not matched to the mobile phase? LCGC 32(11) 854-859 (2014) John W. Dolan

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2014-10. How Much Can I Inject? Part I: Injecting in Mobile Phase

October 1, 2014

Both the volume of the sample injection and the solvent in which the sample is dissolved can affect the appearance of the chromatogram. LCGC 32(10) 780-785 (2014) John W. Dolan

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2013-12. Peak Fronting . . . Some of the Time

December 1, 2013

Why do some peaks front and others don’t in the same method? LCGC 31(12) 992-997 (2013) John W. Dolan

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2012-1. LC Trouble Everywhere

January 1, 2012

No matter where liquid chromatography is used, it is never immune to problems. LCGC 30(1) 36-40 (2012) John W. Dolan

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2011-6. The Case of the Too Big Little Peak

June 1, 2011

What do you do when a peak grows over time?. LCGC 29(6) 486-491 (2011) John W. Dolan

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2005-1. Stay Away from the Cliffs!

January 1, 2005

Does your method have a safety factor? LCGC 23(1) 30-35 (2005) John W. Dolan

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2004-11. My Favorite Shortcuts

November 1, 2004

Simple ways to estimate chromatographic changes. LCGC 22(11) 1074-1080 (2004) John W. Dolan

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2004-1. Broad Peaks

January 1, 2004

Do your peaks need to go on a diet? LCGC 22(1) 26-30 (2004) John W. Dolan

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2001-9. When Ideal Isn’t Practical

September 1, 2001

Sometimes you must sacrifice chromatographic performance to obtain analytical results. LCGC 19(9) 956-960 (2001) Melissa M. Harrington and John W. Dolan

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1999-6. How Much Is Too Much?

June 1, 1999

Just how much sample can you load onto a liquid chromatography column? LCGC 17(6) 508-510 (1999) John W. Dolan

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