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Tag: ghost peaks


2016-10. Reader’s Questions: Gradient Ghost Peaks

October 1, 2016

Interfering peaks of high baseline background can compromise the results of gradient liquid chromatography (LC) separations. LCGC 34(10) 778-785 (2016) John W. Dolan

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2012-5. Extra Chromatographic Peaks – A Case Study

May 1, 2012

What do you do when an unexpected peak appears in the chromatogram? LCGC 30(5) 392-400 (2012) John W. Dolan Erratum: (from 30(7), on p 394, the calculation showed that 0.1% x 0.1% = 0.01%, when in fact is should have been 0.1% x 0.1% = 0.0001%

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2011-5. Ghost Peak Investigation in a Reversed-Phase Gradient LC System

May 1, 2011

Ghost peaks can be difficult to eliminate when minor peaks are important in an LC Separation. This case study shows how to isolate the source of such peaks. LCGC 29(5) 394-400 (2011) Silvia Sadikin, Dee Dee Zhang, Roger Inloes, Sanjeev Redkar, and John W. Dolan

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1999-3. Late Elution and Carryover Peaks — A Case Study

March 1, 1999

What’s the source of an extra peak in the second injection? LCGC 17(3) 230-234 (1999) Jin Y. Huang, Travis Culey, and John W. Dolan

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1998-11. Gradient Background Peaks — A Case Study

November 1, 1998

When peaks appear in a blank gradient, isolating the problem source can be a challenge LCGC 16(11) 992-996 (1998) Michael D. Nelson and John W. Dolan

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1998-2. Ghost Peaks and Aerated Sample Solvent

February 1, 1998

Ghost peaks are one of liquid chromatography’s most aggravating problems LCGC 16(2) 112-118 (1998) Yoshihiro Egi and Atsuro Ueyanagi

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1996-3. Water Problems: A Case Study

March 1, 1996

Sometimes HPLC-grade isn’t pure enough. LCGC 14(3) 202-208 (1996) John W. Dolan, John R. Kern, and Travis Culley

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1992-4. The Case of the Mystery Gradient Peak

April 1, 1992

Sometimes you can solve a problem without gaining the satisfaction of understanding its cause. LCGC 10(4) 294-296 (1992) John W. Dolan

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1988-2. Ghost and Vacancy Peaks

February 1, 1988

LCGC 6(2) 112-116 (1988) John W. Dolan

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1987-6. Gradient Elution Separation Problems, Part II

June 1, 1987

LCGC 5(6) 466-470 (1987) John W. Dolan

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