Several variables can be used to change selectivity in a liquid chromatography (LC) separation. Here we compare the variables in an effort to prioritize which experiments will be most effective. LCGC 35(5) 306-311 (2017) John W. Dolan See also 2017-3 and 2017-4 for remaining articles in this series.
Read More →How to choose another column to try to solve a separation problem. LCGC 29(3) 236-244 (2011) John W. Dolan
Read More →Where to place the blame when something goes wrong. LCGC 27(9) 816-821 (2009) John W. Dolan
Read More →What’s the big deal about a few microliters of volume? LCGC 26(11) 1092-1098 (2008) John W. Dolan
Read More →How to avoid an expensive shot in the dark. LCGC 25(10) 1014-1020 (2007) John W. Dolan
Read More →Getting started on the right foot is important for efficient method development. LCGC 25(7) 632-638 (2007) John W. Dolan
Read More →How much tubing can you get away with? LCGC 23(2) 130-135 (2005) John W. Dolan
Read More →John Dolan answers reader’s questions related to columns and methods. LCGC 19(12) 1192-1196 (2001) John W. Dolan
Read More →Some compounds just won’t stick to the column. LCGC 19(11) 1132-1135 (2001) John W. Dolan
Read More →Simply scaling the gradient won’t always work LCGC 18(12) 1228-1232 (2000) John W. Dolan Erratum: Figure 3 and the accompanying discussion is not quite correct. The correct numbers are (assuming that a 150 x 4.6 mm column has a column volume, Vm = 1.5 mL and a 150 x 2.1 […]
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