In his final column before retirement, John Dolan reminisces about his years as the author of “LC Troubleshooting,” and some of the hcanges that have taken place in liquid chromatography (LC) technology during that time. LCGC 35(10) 746-750 (2017) John W. Dolan *ed. notes: (1) This is John Dolan’s last […]
Read More →The silica-based packing in reversed-phase columns is not inert. Here we consider what happens when the mobile-phase pH is too high or too low. LCGC 34(2) 106-113 (2016) John W. Dolan
Read More →Particulate matter from the sample or the system can cause havoc in the chromatogram. LCGC 33(12) 894-899 (2015) John W. Dolan Errata: Note that there was a transposition error in this and two associated articles. In the referenced table, the words “Symptom” and “Cause” have been reversed. That is, “Cause” […]
Read More →How to get started in the process of identifying the problem source for column-related problems. LCGC 33(11) 844-847 (2015) John W. Dolan Errata: Note that there was a transposition error in this and two associated articles. In the referenced table, the words “Symptom” and “Cause” have been reversed. That is, […]
Read More →No matter where you live or who you work for, you’re likely to encounter one or more of these liquid chromatography (LC) column problems at some point. LCGC 33(9) 694-699 (2015) John W. Dolan
Read More →Some attributes of large molecules make them behave differently from small molecules in reversed-phase separations. LCGC 32(4) 256-261 (2014) John W. Dolan
Read More →Questions from the e-mail bag are considered this month. LCGC 30(9) 828-832 (2012) John W. Dolan
Read More →Retention-time drift, temperature control, and broad peaks from a new column are the topics in this month’s discussion. LCGC 30(8) 634-636 (2012) John W. Dolan
Read More →How do you react to symptoms that indicate your liquid chromatography column has major problems? LCGC 29(10) 908-912 (2011) John W. Dolan
Read More →Responses to a collection of random LC questions. LCGC 26(9) 914-920 (2008) John W. Dolan
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