2021-4. Where Has My Efficiency Gone? Impacts of Extracolumn Peak Broadening on Performance, Part I: Basic Concepts

Dispersion of analyte zones outside of the column often compromises the quality of an LC separation—particularly in smaller columns with smaller particles. We explain basic concepts in extracolumn dispersion from the point of view of an entire instrument.

LCGC 39(4), 159–166 (2021).

Dwight R. Stoll and Ken Broeckhoven